This was done routinely for me because I had high blood pressure at the time. June 6, A kidney function panel is done including a GFR. Even supplements such as fish oil and vitamin D can interact with aspirin.I'm a 15 year old and I'm having unpleasant feeling in my lower back and my urine is a little bit concentrated. Always ask your pharmacist to check your prescription and other OTC medications for aspirin interactions or incompatibilities. In addition, aspirin should not be used by someone who is also taking a prescription blood thinner such as warfarin, Pradaxa, or Xarelto, or another OTC NSAID such as naproxen (Aleve) or ibuprofen (Advil).īefore taking any OTC drug on a regular basis, even low-dose aspirin, be sure to talk with your healthcare provider first to find out if it’s right for you. Those with an allergy to aspirin or salicylates those with a bleeding disorder such as hemophilia or vitamin K deficiency and people with uncontrolled high blood pressure, severe liver or kidney disease, or asthma should avoid using aspirin. Other less common side effects include kidney, liver, and nervous system problems.Īlthough low-dose aspirin is an OTC drug and safe for most people, the FDA recommends that certain individuals not take aspirin in any dose. The most common ones, occurring in up to 10% of people who take aspirin, are an increased tendency to bleed and stomach upset, including heartburn, nausea, vomiting, or bleeding in the stomach. Aspirin Isn’t Right for EveryoneĮven in low doses, aspirin can have significant side effects. Recent research has also found regular aspirin use to be associated with lower rates of breast, prostate, lung, and ovarian cancer. It is aspirin’s anti-inflammatory action that also makes it useful in the prevention of colon cancer and in preeclampsia, a serious condition of pregnancy believed to result from an inflammatory response. Aspirin prevents these prostaglandins from forming, reducing inflammation. Prostaglandins increase blood flow to the injury, leading to the redness, heat, and swelling associated with inflammation. When an injury occurs, the immune system is activated, and compounds called prostaglandins form in the area surrounding the injury. Similar to the formation of blood clots, inflammation is the body’s natural response to injury. Anti-Inflammatory Actions KeyĪspirin is also a nonsteroidal anti-inflammatory drug (NSAID), which means that it reduces inflammation, although it is not a steroid like cortisone or prednisone. Speak with your physician before starting low-dose aspirin for prevention. Low-dose aspirin has been shown to reduce the risk of a first heart attack but has not been definitively proven to reduce the risk of a stroke. If you have had a heart attack or stroke, your doctor may prescribe low-dose aspirin to prevent a second event.
Aspirin stops clots from forming by preventing the platelets from clumping together. Blood clots can form in damaged vessels of the heart or the brain, and these can block blood to the tissue and cause a heart attack or stroke. The fibrin creates a net-like structure that holds the forming clot together. When a blood vessel is damaged, sticky cells called platelets begin to clump together, while proteins in the blood form strands of fibrin. Under normal circumstances, the body develops a blood clot to stop the loss of blood after an injury. Most heart attacks and strokes happen when a blood clot forms and blocks blood flow in an artery. Low-dose aspirin refers to dosages between 81 mg and 325 mg taken every day to prevent heart attacks, strokes, and colon cancer. The regular adult dosage is 650 mg taken every 4 hours when needed to treat pain, inflammation, and fever caused by a variety of ailments. In 1897, the Bayer company in Germany developed a synthetic version called acetylsalicylic acid and named it aspirin. Taken for pain relief for over 2,000 years, its active ingredient, salicin, is in the leaves and bark of the willow tree. A Little Does a LotĪspirin is one of the oldest, most widely used drugs in the world.
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